Topical TMPRSS2 inhibition prevents SARS-CoV-2 infection in differentiated human airway cultures

There is an urgent need to develop novel therapeutic strategies to prevent viral transmission and COVID-19 disease—we show that topical application of camostat, a TMPRSS2 inhibitor, could be a simple, safe, and effective strategy for restricting upper airway infection. Background: There are limited...

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Hlavní autoři:	Wenrui Guo, Linsey M Porter, Thomas WM Crozier, Matthew Coates, Akhilesh Jha, Mikel McKie, James A Nathan, Paul J Lehner, Edward JD Greenwood, Frank McCaughan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Life Science Alliance LLC 2022-04-01
Edice:	Life Science Alliance
On-line přístup:	https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202101116
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