Simvastatin modulates mesenchymal stromal cell proliferation and gene expression.

Statins are widely used hypocholesterolemic drugs that block the mevalonate pathway, responsible for the biosysnthesis of cholesterol. However, statins also have pleiotropic effects that interfere with several signaling pathways. Mesenchymal stromal cells (MSC) are a heterogeneous mixture of cells t...

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Hlavní autoři:	Dalila Lucíola Zanette, Julio Cesar Cetrulo Lorenzi, Rodrigo Alexandre Panepucci, Patricia Vianna Bonini Palma, Daiane Fernanda Dos Santos, Karen Lima Prata, Wilson Araújo Silva
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2015-01-01
Edice:	PLoS ONE
On-line přístup:	http://europepmc.org/articles/PMC4395223?pdf=render
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