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Amidation of glutamate residues in mycobacterial peptidoglycan is essential for cell wall cross-linking

IntroductionMycobacteria assemble a complex cell wall with cross-linked peptidoglycan (PG) which plays an essential role in maintenance of cell wall integrity and tolerance to osmotic pressure. We previously demonstrated that various hydrolytic enzymes are required to remodel PG during essential pro...

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Principais autores: Moagi T. Shaku, Karl L. Ocius, Alexis J. Apostolos, Marcos M. Pires, Michael S. VanNieuwenhze, Neeraj Dhar, Bavesh D. Kana
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-08-01
Serier:Frontiers in Cellular and Infection Microbiology
Fag:
MurT-GatD complex
peptidoglycan biosynthesis
peptidoglycan amidation
peptidoglycan cross-linking
peptidoglycan remodelling
Online adgang:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1205829/full
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