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Low unspliced cell-associated HIV RNA in early treated adolescents living with HIV on long suppressive ART

IntroductionInitiation of antiretroviral treatment (ART) in patients early after HIV-infection and long-term suppression leads to low or undetectable levels of HIV RNA and cell-associated (CA) HIV DNA and RNA. Both CA-DNA and CA-RNA, overestimate the size of the HIV reservoir but CA-RNA as well as p...

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Hlavní autoři: Kathleen Gärtner, Sara Domínguez-Rodríguez, Judith Heaney, Triantafylia Gkouleli, Paul Grant, Karim Dorgham, Delphine Sauce, Cathia Soulie, Eloise J. Busby, Denise M. O’Sullivan, Moira Spyer, Johannes C. Botha, Maria Angeles Muñoz-Fernandez, Alfredo Tagarro, Nicola Cotugno, Jim F. Huggett, Nigel Klein, Paolo Palma, Pablo Rojo Conejo, Caroline Foster, Carlo Giaquinto, Paolo Rossi, Deborah Persaud, Anita De Rossi, Anne-Geneviève Marcelin, Eleni Nastouli
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2024-02-01
Edice:Frontiers in Immunology
Témata:
HIV-1
adolescents
early treated
suppressed
cell-associated RNA
cell-associated DNA
On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1334236/full
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