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geneBasis: an iterative approach for unsupervised selection of targeted gene panels from scRNA-seq

Abstract scRNA-seq datasets are increasingly used to identify gene panels that can be probed using alternative technologies, such as spatial transcriptomics, where choosing the best subset of genes is vital. Existing methods are limited by a reliance on pre-existing cell type labels or by difficulti...

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Detaylı Bibliyografya
Asıl Yazarlar: Alsu Missarova, Jaison Jain, Andrew Butler, Shila Ghazanfar, Tim Stuart, Maigan Brusko, Clive Wasserfall, Harry Nick, Todd Brusko, Mark Atkinson, Rahul Satija, John C. Marioni
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2021-12-01
Seri Bilgileri:Genome Biology
Online Erişim:https://doi.org/10.1186/s13059-021-02548-z
Etiketler: Etiketle
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