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Mimicry-based strategy between human and commensal antigens for the development of a new family of immune therapies for cancer

Background Molecular mimicry between commensal bacterial antigens and tumor-associated antigens (TAAs) has shown potential in enhancing antitumor immune responses. This study leveraged this concept using commensal bacterial antigens, termed OncoMimics, to induce TAA-derived peptide (TAAp)-specific c...

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Autors principals: Agostina Stradella, Francois Ghiringhelli, Ana Maia, Cécile Gouttefangeas, Ulrich Herrlinger, Maria Vieito, Ahmed Idbaih, Ghazaleh Tabatabai, Olivier Adotevi, Alice Talpin, Jennifer Martinez, Wolfgang Wick, Laura Boullerot, Jerome Kervevan, Lucie Aubergeon, Diana Bachrouche, Chloé Ventujol, Léa Bernard, Amandine Manteau, Christophe Bonny, Laurent Chene, Iris Mildenberger, Michael C Burger, Jean-Marie Carpier, Guillaume Kulakowski, Camille Gaal, Francesco Strozzi, Coline Billerey, Ludivine Amable, Tifanny Mersceman, Alexandrine Garnier, Càtia Oliveira, Carolina Calderon, Michaël Bonnet, Julie Noguerol, Karl Laviolette, Marine Malfroy, Gregoire Chevalier, Olivier Joffre, David A. Reardon, Joao Gamelas Magalhaes
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2025-02-01
Col·lecció:Journal for ImmunoTherapy of Cancer
Accés en línia:https://jitc.bmj.com/content/13/2/e010192.full
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