CRL4DCAF12 regulation of MCMBP ensures optimal licensing of DNA replication

Abstract The minichromosome maintenance (MCM2-7) protein complexes are central drivers of genome duplication. Distinct protein pools, parental and nascent MCMs, and their precise equilibrium are essential to sustain error-free DNA replication. However, the mechanism responsible for generating these...

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Principais autores:	Anoop Kumar Yadav, Alikhan Abdirov, Katarina Ondruskova, Simran Negi, Kristina Jamrichova, Karolina Kolarova, Nikol Dibus, Jana Krejci, Hana Polasek-Sedlackova, Lukas Cermak
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Nature Portfolio 2025-10-01
סדרה:	Nature Communications
גישה מקוונת:	https://doi.org/10.1038/s41467-025-64258-5
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