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RNA chain length and stoichiometry govern surface tension and stability of protein-RNA condensates

Summary: Proteomic studies have shown that cellular condensates are frequently enriched in diverse RNA molecules, which is suggestive of mechanistic links between phase separation and transcriptional activities. Here, we report a systematic experimental and computational study of thermodynamic lands...

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Autors principals: Rabia Laghmach, Ibraheem Alshareedah, Matthew Pham, Muralikrishna Raju, Priya R. Banerjee, Davit A. Potoyan
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2022-04-01
Col·lecció:iScience
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2589004222003753
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