Statistical analysis plan for the OPTIMUM study: optimising immunisation using mixed schedules, an adaptive randomised controlled trial of a mixed whole-cell/acellular pertussis vaccine schedule

Abstract Objective The purpose of this double-blind, randomised, controlled trial is to compare allergic outcomes in children following vaccination with acellular pertussis (aP) antigen (standard of care in Australia) given at 2 months of age versus whole cell pertussis (wP) in the infant vaccine sc...

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Principais autores:	James A. Totterdell, Gladymar Perez Chacon, Marie J. Estcourt, Mark Jones, Peter Richmond, Thomas L. Snelling, Julie A. Marsh
格式:	Artigo
語言:	Inglês
出版:	BMC 2022-02-01
叢編:	Trials
主題:	Adaptive design Statistical analysis plan Randomised controlled trial Pertussis vaccine Food allergy
在線閱讀:	https://doi.org/10.1186/s13063-021-05874-6
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