Functional significance of the rare rs35667974 IFIH1 gene polymorphism, associated with multiple autoimmune diseases, using a structural biological approach

Autoimmune diseases, which affect approximately 5% of human population, are a range of diseases in which the immune response to self-antigens results in damage or dysfunction of tissues. Recent genome wide association studies (GWAS) have successfully identified novel autoimmune disease-associated lo...

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Autori principali:	Maria I. Zervou, Athena C. Andreou, Elias E. Eliopoulos, George N. Goulielmos
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis Group 2022-09-01
Serie:	Autoimmunity
Soggetti:	autoimmune diseases gene polymorphism three-dimensional structure interferon induced with helicase c domain 1 (ifih1) mda5
Accesso online:	http://dx.doi.org/10.1080/08916934.2022.2103799
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