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Dipeptidylpeptidase 4 promotes survival and stemness of acute myeloid leukemia stem cells

Summary: Leukemic-stem-cell-specific targeting may improve the survival of patients with acute myeloid leukemia (AML) by avoiding the ablative effects of standard regimens on normal hematopoiesis. Herein, we perform an unbiased screening of compounds targeting cell surface proteins and identify clin...

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Autori principali: Chen Wang, Ravi Nistala, Min Cao, Yi Pan, Madelaine Behrens, Donald Doll, Richard D. Hammer, Puja Nistala, Hui-Ming Chang, Edward T.H. Yeh, XunLei Kang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2023-02-01
Serie:Cell Reports
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Accesso online:http://www.sciencedirect.com/science/article/pii/S221112472300116X
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