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Hypoxia-Conditioned MSC Exosomes Upregulate mTORC1 and Suppress MMP-2 in a UV-B–Induced Collagen Loss Rat Model

Background: Ultraviolet-B (UV-B) radiation accelerates photoaging by disrupting extracellular matrix (ECM) homeostasis through dysregulation of mechanistic target of rapamycin complex 1 (mTORC1) and upregulation of matrix metalloproteinase-2 (MMP-2). This study evaluated the effects of exosomes of h...

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Autores principales: Anggrila Sekar Fadhillah, Agung Putra, Titiek Sumarawati, Eko Setiawan
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell and BioPharmaceutical Institute 2026-03-01
Colección:MCBS (Molecular and Cellular Biomedical Sciences)
Acceso en línea:https://cellbiopharm.com/ojs/index.php/MCBS/article/view/749
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