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Comparative analysis of OECD guideline data and Tox21 assays to improve reproductive and developmental toxicity prediction

Abstract Reproductive and developmental toxicities pose major challenges in chemical safety evaluation because adverse effects can span generations. Conventional in vivo OECD Test Guideline (TG) assays provide robust hazard characterization but require large animal cohorts and extended study periods...

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Bibliográfalaš dieđut
Váldodahkkit: Hee Jung Kwon, Hyomin Lee, Sunyi Lee, Woori Ko, Shin Jea Yun, Yoshihiro Uesawa, Joohee Jung
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Nature Portfolio 2025-12-01
Ráidu:Scientific Reports
Fáttát:
Liŋkkat:https://doi.org/10.1038/s41598-025-33419-3
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