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Exploring the mechanism of Alisma orientale for the treatment of pregnancy induced hypertension and potential hepato-nephrotoxicity by using network pharmacology, network toxicology, molecular docking and molecular dynamics simulation

Background: Pregnancy-induced Hypertension (PIH) is a disease that causes serious maternal and fetal morbidity and mortality. Alisma Orientale (AO) has a long history of use as traditional Chinese medicine therapy for PIH. This study explores its potential mechanism and biosafety based on network ph...

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Principais autores: Yilin Liao, Yiling Ding, Ling Yu, Cheng Xiang, Mengyuan Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-11-01
coleção:Frontiers in Pharmacology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2022.1027112/full
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