Alkaline Phosphatase Supplementation During Hypothermic and Normothermic Machine Perfusion Improves Metabolic Dysfunction in a Porcine Model of Donor Kidney Preservation

Background. Kidney preservation techniques, such as hypothermic machine perfusion (HMP), improve graft outcomes in deceased-donor kidney transplantation by pausing graft metabolism and ameliorated ischemia–reperfusion injury (IRI) but do not completely eliminate injury. Alkaline phosphatase (ALP) ha...

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Principais autores:	Thei S. Steenvoorden, MD, Juan Miguel Tellez Garcia, MD, Joost W. van der Heijden, MD, PhD, Frederike Bemelman, MD, PhD, Janneke A. J. Rood, MD, PhD, Sandrine Florquin, MD, PhD, Alessandra Tammaro, MSc, PhD, Henri Leuvenink, MSc, PhD, Liffert Vogt, MD, PhD
格式:	Artigo
语言:	Inglês
出版:	Wolters Kluwer 2026-04-01
丛编:	Transplantation Direct
在线阅读:	http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001929
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