Cathelicidin CATH-2 suppresses the NF-κB/ROS/NLRP3 signaling pathway via regulating mTOR-dependent autophagy during Streptococcus suis infection

Abstract Cathelicidin CATH-2 has been reported to exert potent anti-inflammatory activity in different species though neutralizing stimuli such as lipopolysaccharide (LPS) and lipoteichoic acid (LTA). CATH-2 has been shown to inhibit Streptococcus suis (S. suis)-induced activation of dendritic cells...

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Detalhes bibliográficos

Principais autores:	Liuyi Xu, Yilin Lu, Shichao Xu, Yuqian Liu, Hongdou Liu, Tingting Zhang, Yandi Pan, Yi Lu, Zhouyuan Wang, Xuefeng Cao, Zhiwei Li, Rendong Fang, Lianci Peng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-01-01
coleção:	Veterinary Research
Assuntos:	Cathelicidin-2 Streptococcus suis anti-inflammatory response autophagy
Acesso em linha:	https://doi.org/10.1186/s13567-025-01694-7
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