The case for selection at CCR5-Delta32.
The C-C chemokine receptor 5, 32 base-pair deletion (CCR5-Delta32) allele confers strong resistance to infection by the AIDS virus HIV. Previous studies have suggested that CCR5-Delta32 arose within the past 1,000 y and rose to its present high frequency (5%-14%) in Europe as a result of strong posi...
Guardat en:
| Format: | Artigo |
|---|---|
| Idioma: | Inglês |
| Publicat: |
Public Library of Science (PLoS)
2005-11-01
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| Col·lecció: | PLoS Biology |
| Accés en línia: | http://dx.doi.org/10.1371/journal.pbio.0030378 |
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