In vitro and in vivo models define a molecular signature reference for human embryonic notochordal cells

Summary: Understanding the emergence of human notochordal cells (NC) is essential for the development of regenerative approaches. We present a comprehensive investigation into the specification and generation of bona fide NC using a straightforward pluripotent stem cell (PSC)-based system benchmarke...

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Hlavní autoři:	Julie Warin, Nicolas Vedrenne, Vivian Tam, Mengxia Zhu, Danqing Yin, Xinyi Lin, Bluwen Guidoux-D’halluin, Antoine Humeau, Luce Roseiro, Lily Paillat, Claire Chédeville, Caroline Chariau, Frank Riemers, Markus Templin, Jérôme Guicheux, Marianna A. Tryfonidou, Joshua W.K. Ho, Laurent David, Danny Chan, Anne Camus
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-02-01
Edice:	iScience
Témata:	Biological sciences Biology of human development Developmental biology Natural sciences Omics Transcriptomics
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2589004224002396
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