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The Bushen Huatan formula inhibits TP53-Mediated ferroptosis and modulating lipid metabolism in polycystic ovary syndrome abnormalities rat model

Abstract Background Bushen Huatan Formula (BSHT) shows promise in treating reproductive endocrine disorders, yet its mechanism in polycystic ovary syndrome (PCOS) remains unclear. This study aims to elucidate the specific mechanism of action of BSHT in treating PCOS. Methods PCOS model in rats was e...

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Principais autores: Xingying Li, Xueyuan Hu, Jing Yang, Xiuyong Yue, Lilin Deng, Qian Xiong
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-02-01
Serier:Journal of Ovarian Research
Fag:
Polycystic ovary syndrome
Bushen huatan formula
Ferroptosis
Lipid metabolism
TP53 signaling pathway
Online adgang:https://doi.org/10.1186/s13048-026-01991-5
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