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Case report and literature review: management of Paxlovid (nirmatrelvir/ritonavir)-induced acute tacrolimus toxicity in a patient with systemic lupus erythematosus

Despite the availability of effective vaccines and treatments for SARS-CoV-2, managing COVID-19 in patients with systemic lupus erythematosus (SLE) remains challenging, particularly considering drug-drug interactions (DDIs). Here, we present a case of DDIs between Tacrolimus (Tac) and nirmatrelvir/r...

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Principais autores: Chenxiao Jiang, Xiaodi Yan, Peng Xia, Xuemei Luo, Haoyue Zheng, Hanwen Tong, Yun Liu, Huaijun Zhu, Peng Xu, Jun Wang
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2024-06-01
Series:Frontiers in Pharmacology
Assuntos:
systemic lupus erythematosus
tacrolimus
nirmatrelvir/ritonavir
CYP induction
case report
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fphar.2024.1364121/full
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