Design, Synthesis, and Biological Evaluations of Novel Thiazolo[4,5-d]pyrimidine Corticotropin Releasing Factor (CRF) Receptor Antagonists as Potential Treatments for Stress Related Disorders and Congenital Adrenal Hyperplasia (CAH)

Corticotropin-releasing factor (CRF) is a key neuropeptide hormone that is secreted from the hypothalamus. It is the master hormone of the HPA axis, which orchestrates the physiological and behavioral responses to stress. Many disorders, including anxiety, depression, addiction relapse, and others,...

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Principais autores:	Md Rabiul Islam, Christos Markatos, Ioannis Pirmettis, Minas Papadopoulos, Vlasios Karageorgos, George Liapakis, Hesham Fahmy
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2024-08-01
叢編:	Molecules
主題:	thiazolo[4,5-d]pyrimidines CRF receptor antagonists congenital adrenal hyperplasia (CAH) antalarmin
在線閱讀:	https://www.mdpi.com/1420-3049/29/15/3647
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