Analysis of brain necrosis and secondary cancers after proton beam therapy for pediatric intracranial tumors: a single-center retrospective study

BackgroundProton beam therapy (PBT) is increasingly used for pediatric intracranial tumors due to lower long-term radiation-associated toxicities. However, data on late adverse effects, particularly brain necrosis and intracranial secondary cancer, remain limited. The aim of this study is to evaluat...

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Váldodahkkit:	Masashi Mizumoto, Hiroko Fukushima, Yoshiko Oshiro, Takashi Saito, Ai Muroi, Yuni Yamaki, Sho Hosaka, Masako Inaba, Toshitaka Ishiguro, Masahiko Harada, Hikaru Niitsu, Toshiki Ishida, Taisuke Sumiya, Keiichiro Baba, Masatoshi Nakamura, Haruko Numajiri, Kei Nakai, Hideyuki Sakurai
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2025-09-01
Ráidu:	Frontiers in Oncology
Fáttát:	brain brain necrosis secondary cancer proton beam therapy particle therapy pediatric radiation toxicity
Liŋkkat:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1644839/full
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