Population pharmacokinetic modeling of sulfadimethoxine, sulfadiazine and sulfamethoxazole combined to trimethoprim in pigs

Sulfonamides (S) are old antibiotics combined with trimethoprim (TMP) for synergistic effects against pathogens responsible for a variety of infections in food-producing animals. In growing pigs, the TMP:S ratio is 1:5 based on human TMP/sulfamethoxazole (SMX) dosing which aims to obtain an in vivo...

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Detalhes bibliográficos

Principais autores:	Marine Boulanger, Jean-François Taillandier, Jérôme Henri, Mathias Devreese, Siegrid De Baere, Marlène Lacroix, Aude A. Ferran, Alexis Viel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2025-12-01
coleção:	Veterinary Quarterly
Assuntos:	Combination dosage regimen population pharmacokinetic modeling pigs
Acesso em linha:	https://www.tandfonline.com/doi/10.1080/01652176.2025.2565351
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