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Woxuanzhongzhou formula improves DHEAS and high-fat diet-induced IR and anovulatory mice via AMPK/PGC1- α/Irisin pathway

Abstract Background Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in women of reproductive age. Anovulation is one of the most important clinical features of PCOS, and insulin resistance (IR) is one of the critical pathogenic factors. Woxuanzhongzhou (WXZZ) is a tradi...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Haijuan Liu, Guohua Wang, Conglu Sui, Yanan Guo, Xiangyu He
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-01-01
Schriftenreihe:Journal of Ovarian Research
Schlagworte:
Polycystic ovary syndrome
Insulin resistance
Irisin
FNDC5
AMPK
PGC1-α
Online-Zugang:https://doi.org/10.1186/s13048-025-01587-5
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