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Antigen binding characteristics of immunoglobulin free light chains: crosslinking by antigen is essential to induce allergic inflammation.

Beside the production of complete immunoglobulins IgG, IgE, IgA, IgM and IgD, consisting of tetrameric heterodimers of immunoglobulin heavy and light chains, B cells also secrete immunoglobulin free light chains (Ig-fLC). Previous studies showed that Ig-fLCs are able to induce immediate hypersensiti...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Marco Thio, Tom Groot Kormelink, Marcel J Fischer, Bart R Blokhuis, Frans P Nijkamp, Frank A Redegeld
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Public Library of Science (PLoS) 2012-01-01
Цуврал:PLoS ONE
Онлайн хандалт:http://europepmc.org/articles/PMC3401207?pdf=render
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