Metabolic shifts in murine inner ears mimicking erythrocytes and plasma reveal diagnostics and early predictors for age-related hearing loss

Summary: Age-related hearing loss (ARHL) is a major public health concern, driven by the interplay of multiple factors. Here, we reveal spatiotemporal metabolic shifts in murine inner ears mirroring erythrocytes and plasma. Isotope-labeled glucose tracing demonstrates a metabolic rerouting favoring...

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Hlavní autoři:	Qi Guo, Zhenjiang Li, Cheng Luo, Changhan Chen, Xi Long, Yidan Wang, Qingfen Qiang, Fang Yu, Wuping Liu, Yujin Zhang, Rodney E. Kellems, Yang Xia
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-09-01
Edice:	iScience
Témata:	Diagnostics Human metabolism
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2589004225015469
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