Engineering the tumor microenvironment: oncolytic NDV to facilitate CAR-T cell therapy

Abstract Chimeric antigen receptor (CAR)-T cell therapy has achieved significant progress in the treatment of hematologic cancers but continues to face major obstacles in solid tumors, including antigen heterogeneity, limited infiltration, and an immunosuppressive tumor microenvironment (TME). Oncol...

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Podrobná bibliografie

Hlavní autoři:	Mei Wang, Ke Jiang, Alexandra Aicher, Christopher Heeschen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-11-01
Edice:	Journal of Translational Medicine
Témata:	Newcastle disease virus Tumor microenvironment CAR-T cell therapy Oncolytic virus Virotherapy Immunotherapy
On-line přístup:	https://doi.org/10.1186/s12967-025-07342-0
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