CRISPR-Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition

Summary: Human leukocyte antigen (HLA) class-I molecules present fragments of the cellular proteome to the T cell receptor (TCR) of cytotoxic T cells to control infectious diseases and cancer. The large number of combinations of HLA class-I allotypes and peptides allows for highly specific and dedic...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Tom A.W. Schoufour, Anneloes van der Plas - van Duijn, Ian Derksen, Marije Melgers, Jacqueline M.F. van Veenendaal, Claire Lensen, Mirjam H.M. Heemskerk, Jacques Neefjes, Ruud H.M. Wijdeven, Ferenc A. Scheeren
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Elsevier 2024-06-01
Sarja:	iScience
Aiheet:	Biochemistry Bioinformatics Biological sciences Immunology Natural sciences
Linkit:	http://www.sciencedirect.com/science/article/pii/S2589004224013452
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