A <named-content content-type="genus-species">Trypanosoma brucei</named-content> ORFeome-Based Gain-of-Function Library Identifies Genes That Promote Survival during Melarsoprol Treatment

ABSTRACT Trypanosoma brucei is an early branching protozoan parasite that causes human and animal African trypanosomiasis. Forward genetics approaches are powerful tools for uncovering novel aspects of trypanosomatid biology, pathogenesis, and therapeutic approaches against trypanosomiasis. Here, we...

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Autors principals:	McKenzie Carter, Stephanie Gomez, Sam Gritz, Stephen Larson, Eugenia Silva-Herzog, Hee-Sook Kim, Danae Schulz, Galadriel Hovel-Miner
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology 2020-10-01
Col·lecció:	mSphere
Matèries:	forward genetics ORFeome Trypanosoma drug resistance mechanisms parasitology redox signaling
Accés en línia:	https://journals.asm.org/doi/10.1128/mSphere.00769-20
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