The Inhibition of Antibiotic Production in Streptomyces coelicolor Over-Expressing the TetR Regulator SCO3201 IS Correlated With Changes in the Lipidome of the Strain

In condition of over-expression, SCO3201, a regulator of the TetR family was previously shown to strongly inhibit antibiotic production and morphological differentiation in Streptomyces coelicolor M145. In order to elucidate the molecular processes underlying this interesting, but poorly understood...

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Hlavní autoři:	Jun Zhang, Qiting Liang, Zhongheng Xu, Miao Cui, Qizhong Zhang, Sonia Abreu, Michelle David, Clara Lejeune, Pierre Chaminade, Marie-Joelle Virolle, Delin Xu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2020-06-01
Edice:	Frontiers in Microbiology
Témata:	Streptomyces coelicolor antibiotics TetR regulator fatty acid metabolism RNA-seq
On-line přístup:	https://www.frontiersin.org/article/10.3389/fmicb.2020.01399/full
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