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NLRP3 inflammasome as a therapeutic target in autoimmune inner ear disease

Autoimmune inner ear disease (AIED) is a rare cause of bilateral, progressive sensorineural hearing loss (SNHL) that often responds to immunosuppressive therapy. Once considered primarily a T cell–driven condition, recent evidence underscores the importance of innate immunity, with the NLRP3 inflamm...

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Autori principali: Vincent G. Yuan, Peter Kullar, Anping Xia, Peter L. Santa Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2025-11-01
Serie:Frontiers in Audiology and Otology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fauot.2025.1673518/full
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