Individual islet respirometry reveals functional diversity within the islet population of mice and human donors

Objective: Islets from the same pancreas show remarkable variability in glucose sensitivity. While mitochondrial respiration is essential for glucose-stimulated insulin secretion, little is known regarding heterogeneity in mitochondrial function at the individual islet level. This is due in part to...

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Hlavní autoři:	Evan P. Taddeo, Linsey Stiles, Samuel Sereda, Eleni Ritou, Dane M. Wolf, Muhamad Abdullah, Zachary Swanson, Josh Wilhelm, Melena Bellin, Patrick McDonald, Kacey Caradonna, Andrew Neilson, Marc Liesa, Orian S. Shirihai
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2018-10-01
Edice:	Molecular Metabolism
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2212877818304861
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