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Derivation of transgene-free human induced pluripotent stem cells from human peripheral T cells in defined culture conditions.

Recently, induced pluripotent stem cells (iPSCs) were established as promising cell sources for revolutionary regenerative therapies. The initial culture system used for iPSC generation needed fetal calf serum in the culture medium and mouse embryonic fibroblast as a feeder layer, both of which coul...

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Huvudupphov: Yoshikazu Kishino, Tomohisa Seki, Jun Fujita, Shinsuke Yuasa, Shugo Tohyama, Akira Kunitomi, Ryota Tabei, Kazuaki Nakajima, Marina Okada, Akinori Hirano, Hideaki Kanazawa, Keiichi Fukuda
Materialtyp: Artigo
Språk:Inglês
Utgiven: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Länkar:http://europepmc.org/articles/PMC4019536?pdf=render
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