H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs

Summary: Histone variant H2A.Z occupies the promoters of active and poised, bivalent genes in embryonic stem cells (ESCs) to regulate developmental programs, yet how it contributes to these contrasting states is poorly understood. Here, we investigate the function of H2A.Z.1 monoubiquitylation (H2A....

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Autores principales:	Lauren E. Surface, Paul A. Fields, Vidya Subramanian, Russell Behmer, Namrata Udeshi, Sally E. Peach, Steven A. Carr, Jacob D. Jaffe, Laurie A. Boyer
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2016-02-01
Colección:	Cell Reports
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2211124715015569
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