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Antiviral Activities of HIV-1-Specific Human Broadly Neutralizing Antibodies Are Isotype-Dependent

Broadly neutralizing antibodies (bNAbs) offer promising opportunities for preventing HIV-1 infection. The protection mechanisms of bNAbs involve the Fc domain, as well as their Fab counterpart. Here, different bNAb isotypes including IgG1, IgA1, IgA2, and IgA122 (IgA2 with the hinge of IgA1) were ge...

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Bibliográfalaš dieđut
Váldodahkkit: Blandine Noailly, Melyssa Yaugel-Novoa, Justine Werquin, Fabienne Jospin, Daniel Drocourt, Thomas Bourlet, Nicolas Rochereau, Stéphane Paul
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2022-06-01
Ráidu:Vaccines
Fáttát:
Liŋkkat:https://www.mdpi.com/2076-393X/10/6/903
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