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Prolonged Release of Anti-inflammatory Diclofenac Sodium from <i>In Situ</i> Loaded Thermosensitive Chitosan Hydrogels for Localized Applications

Previous work developed a thermosensitive hydrogel from chitosan (CS) and β-glycerophosphate (GP) loaded with diclofenac sodium (DIC) using a post-loading method. The hydrogel as a wound dressing exhibited burst release of DIC within 5 h, rendering it suitable for immediate anti-inflammatory treatme...

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Principais autores: Nga Hoang Nguyen Do, Ha Vu Le, Khoa Dang Nguyen, Anh Cam Ha
Formato: Artigo
Idioma:Inglês
Publicado em: Department of Chemistry, Universitas Gadjah Mada 2025-10-01
coleção:Indonesian Journal of Chemistry
Assuntos:
thermosensitive hydrogel
diclofenac sodium
in situ loading
characterization
release profile
Acesso em linha:https://jurnal.ugm.ac.id/ijc/article/view/106833
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