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Epigenetic Dynamics in Reprogramming to Dopaminergic Neurons for Parkinson's Disease

Abstract Direct lineage reprogramming into dopaminergic (DA) neurons holds great promise for the more effective production of DA neurons, offering potential therapeutic benefits for conditions such as Parkinson's disease. However, the reprogramming pathway for fully reprogrammed DA neurons remains l...

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Principais autores: Byounggook Cho, Junyeop Kim, Sumin Kim, Saemin An, Yerim Hwang, Yunkyung Kim, Daeyeol Kwon, Jongpil Kim
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2024-11-01
Serier:Advanced Science
Fag:
cellular trajectory
direct reprogramming
induced dopaminergic neuron
Parkinson disease
Online adgang:https://doi.org/10.1002/advs.202403105
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