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Herpesvirus Entry Mediator Binding Partners Mediate Immunopathogenesis of Ocular Herpes Simplex Virus 1 Infection

ABSTRACT Ocular herpes simplex virus 1 (HSV-1) infection leads to an immunopathogenic disease called herpes stromal keratitis (HSK), in which CD4+ T cell-driven inflammation contributes to irreversible damage to the cornea. Herpesvirus entry mediator (HVEM) is an immune modulator that activates stim...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Seo J. Park, Rachel E. Riccio, Sarah J. Kopp, Igal Ifergan, Stephen D. Miller, Richard Longnecker
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020-06-01
Schriftenreihe:mBio
Schlagworte:
BTLA
CD160
HSV
HVEM
immunopathogenesis
herpesvirus stromal keratitis
Online-Zugang:https://journals.asm.org/doi/10.1128/mBio.00790-20
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