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Brief Report: Real-World Efficacy and Safety of Sotorasib in U.S. Veterans with KRAS G12C-Mutated NSCLC

Introduction: The KRAS G12C inhibitor sotorasib was approved for treating advanced NSCLC in the second line or later on the basis of the CodeBreaK100 trial. Nevertheless, data on the real-world efficacy and safety of sotorasib, and to its optimal dose, remain limited. Methods: Patients treated with...

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Principais autores: Katherine I. Zhou, MD, PhD, Chenyu Lin, MD, Chin-Lin Tseng, MPH, Nithya Ramnath, MBBS, Jonathan E. Dowell, MD, Michael J. Kelley, MD
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-05-01
coleção:JTO Clinical and Research Reports
Assuntos:
Sotorasib
KRAS
KRAS G12C
Non-small cell lung cancer (NSCLC)
Real-world
Dose reduction
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2666364324000407
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