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Epithelial and Neutrophil Interactions and Coordinated Response to Shigella in a Human Intestinal Enteroid-Neutrophil Coculture Model

ABSTRACT Polymorphonuclear neutrophils (PMN) are recruited to the gastrointestinal mucosa in response to inflammation, injury, and infection. Here, we report the development and the characterization of an ex vivo tissue coculture model consisting of human primary intestinal enteroid monolayers and P...

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Principais autores: Jose M. Lemme-Dumit, Michele Doucet, Nicholas C. Zachos, Marcela F. Pasetti
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2022-06-01
Serier:mBio
Fag:
enteroid
host-pathogen interactions
human
intestinal mucosa
neutrophils
Shigella
Online adgang:https://journals.asm.org/doi/10.1128/mbio.00944-22
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