443 Team Science
OBJECTIVES/GOALS: T develop a novel PROTAC to deplete BRK to inhibit tumorigenesis and metastasis, which is unattainable by using tradition kinase inhibitors. METHODS/STUDY POPULATION: We will design, synthesize, and evaluate BRK-specific PROTACs to study both catalytic and scaffolding properties of...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cambridge University Press
2023-04-01
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| coleção: | Journal of Clinical and Translational Science |
| Acesso em linha: | https://www.cambridge.org/core/product/identifier/S2059866123004703/type/journal_article |
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