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Self-supervised attention-based deep learning for pan-cancer mutation prediction from histopathology

Abstract The histopathological phenotype of tumors reflects the underlying genetic makeup. Deep learning can predict genetic alterations from pathology slides, but it is unclear how well these predictions generalize to external datasets. We performed a systematic study on Deep-Learning-based predict...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Oliver Lester Saldanha, Chiara M. L. Loeffler, Jan Moritz Niehues, Marko van Treeck, Tobias P. Seraphin, Katherine Jane Hewitt, Didem Cifci, Gregory Patrick Veldhuizen, Siddhi Ramesh, Alexander T. Pearson, Jakob Nikolas Kather
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2023-03-01
Schriftenreihe:npj Precision Oncology
Online-Zugang:https://doi.org/10.1038/s41698-023-00365-0
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