CD137 Signaling Modulates Vein Graft Atherosclerosis by Driving T-Cell Activation and Regulating Intraplaque Angiogenesis

Summary: Atherosclerotic vein graft failure still presents a major problem. T-cells have been identified as one of the most abundant immune cell subset in atherosclerotic plaques. Their role, however, remains only partly understood. Using a murine vein graft model for advanced, unstable atherosclero...

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Autors principals:	Alwin de Jong, MD, PhD, Thijs J. Sluiter, BSc, Hendrika A.B. Peters, BSc, Alec Lamens, MSc, J. Wouter Jukema, MD, PhD, Ramon Arens, PhD, Paul.H.A. Quax, PhD, Margreet R. de Vries, PhD
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2025-08-01
Col·lecció:	JACC: Basic to Translational Science
Matèries:	CD137-CD137L signaling costimulation intraplaque angiogenesis T-cells vein graft atherosclerosis
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2452302X25002736
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