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DEAD-Box Helicase 27 Triggers Epithelial to Mesenchymal Transition by Regulating Alternative Splicing of Lipoma-Preferred Partner in Gastric Cancer Metastasis

DEAD-box helicase 27 (DDX27) was previously identified as an important mediator during carcinogenesis, while its role in gastric cancer (GC) is not yet fully elucidated. Here, we aimed to investigate the mechanism and clinical significance of DDX27 in GC. Public datasets were analyzed to determine D...

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Principais autores: Yirong Jin, Suzhen Yang, Xiaoliang Gao, Di Chen, Tingting Luo, Song Su, Yanting Shi, Gang Yang, Lei Dong, Jie Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
coleção:Frontiers in Genetics
Assuntos:
DDX27
gastric cancer metastasis
LPP
alternative splicing
EMT
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fgene.2022.836199/full
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