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GPCR-CARMA3-NF-kappaB Signaling Axis: A Novel Drug Target for Cancer Therapy

G protein-coupled receptors (GPCRs) play pivotal roles in regulating various cellular functions. It has been well established that GPCR activates NF-κB and aberrant regulation of GPCR-NF-κB signaling axis leads to cancers. However, how GPCRs induce NF-κB activation remains largely elusive. Recently,...

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Bibliografiske detaljer
Hovedforfatter: Ji-yuan SUN
Format: Artigo
Sprog:Inglês
Udgivet: China Anti-Cancer Association 2010-06-01
Serier:Cancer Biology & Medicine
Fag:
Online adgang:http://www.cancerbiomed.org/index.php/cocr/article/view/228
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