Leishmania-mediated inhibition of iron export promotes parasite replication in macrophages.
Leishmania parasites infect macrophages, cells that play an important role in organismal iron homeostasis. By expressing ferroportin, a membrane protein specialized in iron export, macrophages release iron stored intracellularly into the circulation. Iron is essential for the intracellular replicati...
Kaydedildi:
| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science (PLoS)
2014-01-01
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| Seri Bilgileri: | PLoS Pathogens |
| Online Erişim: | http://europepmc.org/articles/PMC3907422?pdf=render |
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