Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation
Rapidly proliferating cells switch from oxidative phosphorylation to aerobic glycolysis plus glutaminolysis, markedly increasing glucose and glutamine catabolism. Although Otto Warburg first described aerobic glycolysis in cancer cells >90 years ago, the primary purpose of this metabolic switch r...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
eLife Sciences Publications Ltd
2017-01-01
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| Серии: | eLife |
| Предметы: | |
| Online-ссылка: | https://elifesciences.org/articles/21330 |
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