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The role of skeletal muscle Akt in the regulation of muscle mass and glucose homeostasis

Objective: Skeletal muscle insulin signaling is a major determinant of muscle growth and glucose homeostasis. Protein kinase B/Akt plays a prominent role in mediating many of the metabolic effects of insulin. Mice and humans harboring systemic loss-of-function mutations in Akt2, the most abundant Ak...

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Bibliografische Detailangaben
Hauptverfasser: N. Jaiswal, M.G. Gavin, W.J. Quinn, III, T.S. Luongo, R.G. Gelfer, J.A. Baur, P.M. Titchenell
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019-10-01
Schriftenreihe:Molecular Metabolism
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2212877819305861
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