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The PER Gene Family: Pivotal Regulators Bridging Circadian Clock Disruption to Multifactorial Pathologies

The Period genes, PER1, PER2, and PER3, encode core negative regulators of the mammalian circadian clock and provide an important link between circadian disruption and chronic disease states. Although they belong to the same gene family, PER1, PER2 and PER3 show partially distinct roles in environm...

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Principais autores: Rourong Li, Qiaolu Gao, Yanjun Huang, Ji-An Pan, Liubing Du, Xiaoxue Peng
Formato: Artigo
Idioma:Inglês
Publicado em: European Medical Journal 2026-06-01
coleção:European Medical Journal
Acesso em linha:https://www.emjreviews.com/flagship-journal/article/the-per-gene-family-pivotal-regulators-bridging-circadian-clock-disruption-to-multifactorial-pathologies-j19226/
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