The Effects of Polyhexamethylene Biguanide (PHMB) and TLR Agonists Alone or as Polyplex Nanoparticles against <em>Leishmania infantum</em> Promastigotes and Amastigotes

Dogs are the main reservoir for <i>Leishmania infantum,</i> manifesting from a subclinical to a fatal disease. Limited treatments are available, although new antiparasitics and immunomodulators are pursued. Polyhexamethylene biguanide (PHMB) has a broad antimicrobial spectrum, including antiparasiti...

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Detalhes bibliográficos

Principais autores:	Pamela Martínez-Orellana, Marta Baxarias, Liam Good, Laia Solano-Gallego
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-11-01
coleção:	Veterinary Sciences
Assuntos:	TLR4 agonist TLR9 agonist PHMB <i>Leishmania infantum</i> canine macrophages
Acesso em linha:	https://www.mdpi.com/2306-7381/7/4/179
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